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Split-ends is modulating lipid droplet content in adult <i>Drosophila</i> glial cells and is protective against paraquat toxicity

2020-05-20

Abstract excerpt

<h4>ABSTRACT</h4> Glial cells are early sensors of neuronal injury and are able to store lipids in lipid droplets under oxidative stress conditions. Here, we investigated the glial functions of Spen in the context of Parkinson’s disease (PD). Using a data mining approach, we first found that the human ortholog of spen , SPEN/SHARP belongs to the set of astrocyte-expressed genes which mRNA levels are significant...

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Literature Corpus work
268b703d-76a8-5b6a-b095-19c73fbe5bcc
DOI
10.1101/2020.05.20.101220
Open publication

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Split-ends is modulating lipid droplet content in adult <i>Drosophila</i> glial cells and is protective against paraquat toxicityDOI 10.1101/2020.05.20.101220
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