Article

Gene expression differences in differentially methylated sites associated with HIV status and cocaine use

2024-11-04

Abstract excerpt

<h4>Background</h4> Epigenome studies of human HIV-1 (HIV) in whole blood have uncovered a growing list of differentially methylated genes associated with either HIV acquisition, disease progression, or both. Cocaine use is associated with increased disease severity, and methylation changes in some of the HIV-associated genes mediate this effect. Many of these genes are critical players in innate immune response,...

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Literature Corpus work: a141c89b-fb9c-59c3-949f-fad47ebf7155
DOI: 10.1101/2024.11.03.24316634

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