Article

Comparing low-pass sequencing and genotyping for trait mapping in pharmacogenetics

2019-05-08

Abstract excerpt

Low pass sequencing has been proposed as a cost-effective alternative to genotyping arrays to identify genetic variants that influence multifactorial traits in humans. For common diseases this typically has required both large sample sizes and comprehensive variant discovery. Genotyping arrays are also routinely used to perform pharmacogenetic (PGx) experiments where sample sizes are likely to be significantly sma...

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Literature Corpus work: a127ccce-ca07-5d04-993f-63485b35dc35
DOI: 10.1101/632141

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