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Comparative evaluation of genotyping and low-pass sequencing for pharmacogenetic variant and phenotype inference

2026-08-19

Abstract excerpt

<h4>Background</h4> Pharmacogenetic (PGx) testing can guide drug prescribing but remains limited by the genomic assay used. Genotyping arrays are widely implemented yet limited to predefined variants, whereas low-pass whole-genome sequencing (LP-WGS) is not constrained by fixed probe design and may provide broader PGx variant availability after imputation. <h4>Methods</h4> We compared Illumina Global Screening A...

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Literature Corpus work
6dc5f655-1157-5139-97f6-c3f55203a614
DOI
10.64898/2026.08.18.26360694
Open publication

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Comparative evaluation of genotyping and low-pass sequencing for pharmacogenetic variant and phenotype inferenceDOI 10.64898/2026.08.18.26360694
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