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Article

Low-cost generation of clinical-grade, layperson-friendly pharmacogenetic passports using oligonucleotide arrays.

American journal of human genetics - 1 May 2025

Lanting Pauline, Warmerdam Robert, Slager Jelle, Brugge Harm, Ochi Taichi, Benjamins Marloes, Lopera-Maya Esteban, Jankipersadsing Soesma, Gelderloos-Arends Jody, Teuben Daphne, Hendriksen Dennis, Charbon Bart, Johansson Lennart, Munnink Thijs Oude, de Boer-Veger Nienke, Wilffert Bob, Swertz Morris, Touw Daan, Deelen Patrick, Knoers Nine, Dekens Jackie, Franke Lude

Abstract excerpt

Pharmacogenomic (PGx) information is essential for precision medicine, enabling drug prescriptions to be personalized according to an individual's genetic background. Almost all individuals will carry a genetic marker that affects their drug response, so the ideal drug prescription for these individuals will differ from the population-level guidelines. Currently, PGx information is often not available at first...

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Identifiers

PMID: 40174590
DOI: 10.1016/j.ajhg.2025.03.003
PMCID: PMC12120180

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