Article

Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes

2020-10-29

Abstract excerpt

<h4>SUMMARY</h4> The COVID-19 pandemic has caused significant morbidity and mortality. Currently, there is a critical shortage of proven treatment options and an urgent need to understand the pathogenesis of multi-organ failure and lung damage. Cytokine storm is associated with severe inflammation and organ damage during COVID-19. However, a detailed molecular pathway defining this cytokine storm is lacking, and...

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Literature Corpus work: a0e8a131-72c4-55ee-9c7d-a101157ff43c
DOI: 10.1101/2020.10.29.361048

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