Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SARS-CoV-2 mediated dysregulation in cell signaling events drives the severity of COVID-19

6 Oct 2022

Abstract excerpt

A balance in immune response against an unfamiliar pathogen is crucial to eliminate the infection. A cascade of cell signaling events is immediately activated upon sensing the presence of SARS-CoV-2 by cellular toll like receptors in a natural host response manner against the invading virus. The ultimate aim of such innate immune signaling pathways is to provide a required level of protection to our bodies by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to Immune responses and vaccinations
Share to Long-Term Effects of COVID-19

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36209917
DOI: 10.1016/j.virusres.2022.198962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 mediated dysregulation in cell signaling events drives the severity of COVID-19PMID 36209917Read ↗

Role of toll‐like receptors in modulation of cytokine storm signaling in SARS‐CoV‐2‐induced COVID‐19Semantic proximity Read ↗

COVID-19: The Emerging Immunopathological Determinants for Recovery or DeathSemantic proximity Read ↗

Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targetsSemantic proximity Read ↗

Interplay of TLR4 and SARS-CoV-2: Unveiling the Complex Mechanisms of Inflammation and Severity in COVID-19 InfectionsSemantic proximity Read ↗

Overview of the pathogenesis of COVID‑19 (Review)Semantic proximity Read ↗

Beneficial and Detrimental Effects of Cytokines during Influenza and COVID-19Semantic proximity Read ↗

Therapeutic Approaches for COVID-19 Based on the Dynamics of Interferon-mediated Immune ResponsesSemantic proximity Read ↗

SARS-CoV-2 and the host-immune responseSemantic proximity Read ↗

Mechanistic insight into the protective and pathogenic immune-responses against SARS-CoV-2.Semantic proximity Read ↗

The dual role of toll-like receptors in COVID-19: Balancing protective immunity and immunopathogenesisSemantic proximity Read ↗

Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanismSemantic proximity Read ↗

Mechanistic modeling of the SARS-CoV-2 and immune system interplay unravels design principles for diverse clinicopathological outcomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.