Article

Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis

2021-05-04

Abstract excerpt

Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively known as cytokine release syndrome (CRS), exemplified by key clinical phenotypes unearthed during the SARS-Cov-2 pandemic. The underlying pathophysiology of CRS remains elusive. We found that FLIP, a protein t...

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Literature Corpus work: 32caba9f-9c56-5701-b560-68127fc8fe91
DOI: 10.1101/2021.05.04.21256298

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