Article

Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli

2022-05-09

Abstract excerpt

<h4>Background: </h4> Palifermin (trade name Kepivance®) is an amino-terminally truncated recombinant human keratinocyte growth factor 1 (KGF-1) with 140 residues that has been produced using Escherichia coli to prevent and treat oral mucositis following radiation or chemotherapy. In this study, an amino-terminally shortened KGF-1 variant with 135 residues was produced and purified in E. coli , and its cell prolif...

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Literature Corpus work: a0b76811-7d8f-5df6-af89-e8d4f5f5f8b5
DOI: 10.21203/rs.3.rs-1598847/v1

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