Article

Prediction of Key Pathological Features in Colorectal Cancer Using a CT-derived Intratumoral Heterogeneity Score (ITHscore)

2026-05-20

Abstract excerpt

<title>Abstract</title> <p> <bold>Objectives:</bold> Intratumoral heterogeneity (ITH) is a fundamental hallmark of colorectal cancer (CRC), driving tumor aggressiveness, histological differentiation, local invasion, and metastatic propensity. This study aimed to develop and validate a novel, quantitative radiomic biomarker—the Intratumoral Heterogeneity Score (ITHscore)—derived from routine preoperative contras...

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Literature Corpus work: a09f4393-d489-5e21-a003-463446486e04
DOI: 10.21203/rs.3.rs-9415389/v1

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