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Novel Paclobutrazol Derivatives as Potential Antifungal and CGRP Receptor Modulators: Synthesis and a Computational Assessment

2025-11-27

Abstract excerpt

<h4>Background: </h4> /Objectives: Escalating resistance to existing antifungal compounds necessitates development of novel bioactive molecules with innovative mechanisms. Paclobutrazol, a triazole-containing plant growth regulator with modest antifungal activity, presents a structurally versatile scaffold amenable to derivatization. This study investigated whether strategic structural modifications could enhance...

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Literature Corpus work
a017ec5e-daae-5298-9417-bcf9d5ca2c28
DOI
10.20944/preprints202511.1951.v1
Open publication

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Novel Paclobutrazol Derivatives as Potential Antifungal and CGRP Receptor Modulators: Synthesis and a Computational AssessmentDOI 10.20944/preprints202511.1951.v1
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