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Network Pharmacology-Guided Discovery of Fungal Autophagy Modulators for Tauopathies: Structural and Proteomic Evidence

2026-07-28

Abstract excerpt

Autophagic clearance of hyperphosphorylated tau is impaired in tauopathies, leading to the progressive accumulation of toxic tau species. Fungal metabolites provide a rich yet largely untapped source of neuroactive molecules with therapeutic potential. Here, we investigated metabolites from Lion’s Mane ( Hericium erinaceus ), Magic Mushrooms ( Psilocybe spp.), and Ergot fungi ( Claviceps spp.) using a computati...

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Literature Corpus work
51406ca5-d9c0-564d-9121-7265820d3282
DOI
10.64898/2026.07.24.740367
Open publication

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Network Pharmacology-Guided Discovery of Fungal Autophagy Modulators for Tauopathies: Structural and Proteomic EvidenceDOI 10.64898/2026.07.24.740367
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