Article

Ancestry-specific rewiring of BCR-MAPK signaling in sarcoidosis B cells

2026-04-22

Abstract excerpt

Sarcoidosis is a heterogenous disease of unknown etiology characterized by non-caseating granulomas. Disease prevalence and presentation vary significantly by ancestry and ranges from acute, self-resolving disease to severe, chronic disease. Following previous reports suggesting B cells in the development and pathogenesis of sarcoidosis, we present here results of single-cell RNA sequencing, supporting B cell invo...

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Literature Corpus work: a00db162-ebc8-5312-acf9-1a9bf11a0b74
DOI: 10.64898/2026.04.20.718985

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