Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets.

doi:10.1186/s13023-025-04097-1

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets.

Orphanet journal of rare diseases - 29 Dec 2025

Ricci Andrea, Andolfi Federica, Sabbatini Daniele, Gozzi Filippo, Betto Giada Di, Ventura Paolo, Buzzetti Elena, Pietrangelo Antonello, Clini Enrico, Tonelli Roberto, Andrisani Dario, de Guzman Marinduque Brent Julius, Bergamini Elisa, Vecchi Chiara, Pegoraro Elena, Gregori Dario, Corradini Elena, Cerri Stefania

Abstract excerpt

INTRODUCTION: Sarcoidosis is an inflammatory disease driven by immune-mediated mechanisms, characterized by the formation of epithelioid cell granulomas and a wide range of clinical manifestations. Its phenotype is the result of a complex interplay of genetic and environmental factors, the precise roles and interactions of which remain poorly defined. AIM: To identify candidate genes and risk loci associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Specimen Banks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black People

Share to European People

Share to Japan

Share to Sarcoidosis

Share to United Kingdom

Share to White

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 41466414
DOI: 10.1186/s13023-025-04097-1
PMCID: PMC12751437

Genes

MVP
ACOXL
ANXA11
ATXN2
BMPR2
CCDC88B
CCL24
CD19
ESYT2
FAM117B
HOMER2
IL23R
PLCL1
PPARG
PUS10
RNF215
UBASH3A

Provenance

PubMed metadata and Literature Corpus relationships.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association for sarcoidosis identifies novel risk loci and genetic heritability in African and European ancestries: a meta-analysis from the Finngen, Million Veteran Program, UK Biobank, and Biobank Japan datasets.PMID 41466414Read ↗

GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosisSemantic proximity Read ↗

Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.Semantic proximity Read ↗

Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibilitySemantic proximity Read ↗

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk.Semantic proximity Read ↗

Genetic predisposition to sarcoidosis.Semantic proximity Read ↗

Genome-wide association study identifies multiple HLA loci for sarcoidosis susceptibility.Semantic proximity Read ↗

A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.Semantic proximity Read ↗

Current Insights in Genetics of Sarcoidosis: Functional and Clinical ImpactsSemantic proximity Read ↗

Whole-exome sequencing identifies rare genetic variations in German families with pulmonary sarcoidosis.Semantic proximity Read ↗

Genetics in sarcoidosis.Semantic proximity Read ↗

High-Density Genetic Mapping Identifies New Susceptibility Variants in Sarcoidosis Phenotypes and Shows Genomic-driven Phenotypic Differences.Semantic proximity Read ↗

Genetics of sarcoidosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.