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Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and Degradation

2020-03-15

Abstract excerpt

Alterations in the expression of glutamate/aspartate transporter (GLAST) have been associated with several neuropathological conditions including Alzheimer’s disease and epilepsy. However, the mechanisms by which GLAST expression is altered are poorly understood. Here we used a combination of pharmacological and genetic approaches coupled with quantitative PCR and Western blot to investigate the mechanism of...

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Literature Corpus work
9fa593e7-b7a5-5fa9-9762-b26adf3490f7
DOI
10.20944/preprints202003.0234.v1
Open publication

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Calcineurin Controls Expression of EAAT1/GLAST in Mouse and Human Cultured Astrocytes through Dynamic Regulation of Protein Synthesis and DegradationDOI 10.20944/preprints202003.0234.v1
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