Article

Succinate Dehydrogenase (SDH)-subunit C regulates muscle oxygen consumption and fatigability in an animal model of pulmonary emphysema

2021-01-22

Abstract excerpt

Patients with pulmonary emphysema often develop locomotor muscle dysfunction, which is independently associated with disability and higher mortality in that population. Muscle dysfunction entails reduced force-generation capacity which partially depends on fibers’ oxidative potential, yet very little mechanistic research has focused on muscle respiration in pulmonary emphysema. Using a recently established animal...

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Literature Corpus work: 9f85b9e5-12f5-5a5b-8de6-639de75e326f
DOI: 10.1101/2021.01.22.427763

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