Article
Skeletal muscle dysfunction in COPD: clinical and laboratory observations.
Clinical science (London, England : 1979) - 17 Aug 2009
Man William D-C, Kemp Paul, Moxham John, Polkey Michael I
Abstract excerpt
COPD (chronic obstructive pulmonary disease), although primarily a disease of the lungs, exhibits secondary systemic manifestations. The skeletal muscles are of particular interest because their function (or dysfunction) not only influences the symptoms that limit exercise, but may contribute directly to poor exercise performance. Furthermore, skeletal muscle weakness is of great clinical importance in COPD as it...
Topics
- Adrenal Cortex Hormones
- Animals
- Disease Models, Animal
- Exercise
- Genetic Predisposition to Disease
- Hormones
- Humans
- Hypercapnia
- Hypoxia
- Muscle, Skeletal
- Muscular Diseases