Article

Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers

2023-01-31

Abstract excerpt

<title>Abstract</title> <p>Immune checkpoint inhibitors (ICI) are highly effective in specific cancers where canonical markers of antitumor immunity are used for patient selection. Novel predictors of T cell-inflammation are needed to identify ICI-responsive tumor subsets in additional cancer types. We investigated associations of a 4-chemokine expression signature (c-Score: CCL4, CCL5, CXCL9, CXCL10) with metric...

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Literature Corpus work: 9f82abf1-482a-540d-8ba3-dbda5a90bd14
DOI: 10.21203/rs.3.rs-2417294/v1

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