Article

Autoimmune hypothyroidism GWAS reveals independent autoimmune and thyroid-specific contributions and an inverse relation with cancer risk

2024-07-08

Abstract excerpt

<title>Abstract</title> <p> The high prevalence of autoimmune hypothyroidism (AIHT) - more than 5% in human populations - provides a unique opportunity to unlock the most complete picture to date of genetic loci that underlie systemic and organ-specific autoimmunity. Using a meta-analysis of 81,718 AIHT cases in FinnGen and the UK Biobank, we dissect associations along axes of thyroid dysfunction and autoimmunit...

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Literature Corpus work: 9f2da966-2f56-5474-82ea-5e40c7de74c8
DOI: 10.21203/rs.3.rs-4626646/v1

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