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Article

Therapeutic drug monitoring of voriconazole and CYP2C19 phenotype for dose optimization in paediatric patients.

European journal of clinical pharmacology - 1 Sept 2023

Hu Lin, Huang Qi, Huang Shiqiong, Feng Zeying

Abstract excerpt

PURPOSE: The objective of this study was to evaluate factors influencing voriconazole (VRC) plasma trough concentrations and provide research data for optimizing VRC dosing in Chinese paediatric patients. METHODS: Medical records of inpatients were reviewed retrospectively. Multivariate linear regression analysis was used to identify the factors contributing to the variability of VRC plasma trough concentrations....

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PMID: 37458772
DOI: 10.1007/s00228-023-03538-9

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