Article

Signatures of recent positive selection in enhancers across 41 human tissues

2019-01-29

Abstract excerpt

Evolutionary changes in enhancers are widely associated with variation in human traits and diseases. However, studies comprehensively quantifying levels of selection on enhancers at multiple evolutionary time points during recent human evolution and how enhancer evolution varies across human tissues are lacking. To address these questions, we integrated a dataset of 41,561 transcribed enhancers active in 41 differ...

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Literature Corpus work: 9ec2b415-d9d2-5031-884f-db0a72fc5f19
DOI: 10.1101/534461

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