Article

Platform-Imprinted Transcriptional and Clonal Remodeling of αβ and γδT Cells After Allogeneic Transplantation

2026-02-10

Abstract excerpt

Immune reconstitution after allogeneic hematopoietic stem cell transplantation is influenced by graft-composition and viral reactivation, but the combined long-term impact on αβ and γδT cells remains unclear. We analyzed a cohort of 213 patients receiving either αβT cell-depleted grafts (n=146; graft engineering that removes donor αβT cells) or T cell-replete grafts (n=67; containing donor T cells). Longitudinal i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9e9fb074-6f09-5553-b488-ad3af4fe64a5
DOI: 10.64898/2026.02.09.704768

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Platform-Imprinted Transcriptional and Clonal Remodeling of αβ and γδT Cells After Allogeneic TransplantationDOI 10.64898/2026.02.09.704768Read

Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantationSemantic proximity Read

T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical responseSemantic proximity Read

Deciphering the Contribution of γδ T Cells to Outcomes in Transplantation.Semantic proximity Read

Spatiotemporal Single-Cell Analysis Reveals T Cell Clonal Dynamics and Phenotypic Plasticity in Human Graft-versus-Host DiseaseSemantic proximity Read

Immunophenotyping of T cells Combined with Vβ antibodies identifies long lasting CMV related T cell Expansions with a consistent TIGIT and PD-1 phenotypeSemantic proximity Read

Genetic T-cell receptor diversity at 1 year following allogeneic hematopoietic stem cell transplantation.Semantic proximity Read

Abundant cytomegalovirus (CMV) reactive clonotypes in the CD8+ T cell receptor alpha repertoire following allogeneic transplantationSemantic proximity Read

CMV serostatus and T-cell repertoire diversity 5 years after allogeneic hematopoietic stem cell transplantationSemantic proximity Read

CMV-Responsive CD4 T Cells Have a Stable Cytotoxic Phenotype Over the First Year Post-Transplant in Patients Without Evidence of CMV Viremia.Semantic proximity Read

Quantitative assessment of T cell repertoire recovery after hematopoietic stem cell transplantation.Semantic proximity Read

Donor T-Cell Repertoire Profiling in Recipient Lymphoid and Parenchyma Organs Reveals GVHD Pathogenesis at Clonal Levels After Bone Marrow Transplantation in Mice.Semantic proximity Read

Distinct Immune Homeostasis Remodeling Patterns after HLA‐Matched and Haploidentical TransplantationSemantic proximity Read