Article

Non-invasive Differentiation of M1 and M2 Activation in Macrophages using Hyperpolarized <sup>13</sup> C MRS of Pyruvate and DHA at 1.47 Tesla

2020-12-02

Abstract excerpt

Macrophage activation, first generalized to the M1/M2 dichotomy, is a complex and central process of the innate immune response. Simply, M1 describes the classical pro-inflammatory activation, leading to tissue damage, and M2 the alternative activation promoting tissue repair. Given the central role of macrophages in multiple diseases, the ability to non-invasively differentiate between M1 and M2 activation states...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9e983a5f-6d66-5603-8690-9cdd123dee5b
DOI: 10.1101/2020.12.02.405845

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Non-invasive Differentiation of M1 and M2 Activation in Macrophages using Hyperpolarized <sup>13</sup> C MRS of Pyruvate and DHA at 1.47 TeslaDOI 10.1101/2020.12.02.405845Read

Primary Human M2 Macrophage Subtypes Are Distinguishable by Aqueous Metabolite Profiles.Semantic proximity Read

Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolismSemantic proximity Read

Biology of macrophage fate decision: Implication in inflammatory disordersSemantic proximity Read

Microglial M1/M2 polarization and metabolic states.Semantic proximity Read

Inflammation driven metabolic regulation and adaptation in macrophages.Semantic proximity Read

Fish Macrophages Show Distinct Metabolic Signatures Upon Polarization.Semantic proximity Read

The Role of Metabolic Remodeling in Macrophage Polarization and Its Effect on Skeletal Muscle Regeneration.Semantic proximity Read

Implication of metabolism in the polarization of tumor-associated-macrophages: the mass spectrometry-based point of view.Semantic proximity Read

Decoding Microglial Polarization and Metabolic Reprogramming in Neurodegenerative Diseases: Implications for Disease Progression and TherapySemantic proximity Read

Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors.Semantic proximity Read

Metabolic influence on macrophage polarization and pathogenesisSemantic proximity Read

The role of immunometabolism in macrophage polarization and its impact on acute lung injury/acute respiratory distress syndromeSemantic proximity Read