Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A pair of co-opted retroviral envelope <i>syncytin</i> genes is required for formation of the two-layered murine placental syncytiotrophoblast

27 Oct 2011

Abstract excerpt

In most mammalian species, a critical step of placenta development is the fusion of trophoblast cells into a multinucleated syncytiotrophoblast layer fulfilling essential fetomaternal exchange functions. Key insights into this process came from the discovery of envelope genes of retroviral origin, the syncytins, independently acquired by the human (syncytin-1 and -2), mouse (syncytin-A and -B), and rabbit...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Pregnancy and preeclampsia studies
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22032925
DOI: 10.1073/pnas.1112304108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pair of co-opted retroviral envelope <i>syncytin</i> genes is required for formation of the two-layered murine placental syncytiotrophoblastPMID 22032925Read ↗

Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene.Semantic proximity Read ↗

Sodium-dependent phosphate transporter PiT1/SLC20A1 as the receptor for the endogenous retroviral envelope syncytin-B involved in mouse placenta formationSemantic proximity Read ↗

Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in MuridaeSemantic proximity Read ↗

Endogenous retroviral syncytin: compilation of experimental research on syncytin and its possible role in normal and disturbed human placentogenesisSemantic proximity Read ↗

The Role of Syncytin in Placental Angiogenesis and Fetal GrowthSemantic proximity Read ↗

The role of syncytins in human reproduction and reproductive organ cancersSemantic proximity Read ↗

TFEB controls syncytiotrophoblast differentiationSemantic proximity Read ↗

Human endogenous retrovirus-W envelope (syncytin) is expressed in both villous and extravillous trophoblast populationsSemantic proximity Read ↗

Expression of Syncytin 1 (HERV-W), in the preimplantation human blastocyst, embryonic stem cells and trophoblast cells derived<i>in vitro</i>Semantic proximity Read ↗

Differential Evolutionary Fate of an Ancestral Primate Endogenous Retrovirus Envelope Gene, the EnvV Syncytin, Captured for a Function in PlacentationSemantic proximity Read ↗

Identification of an endogenous retroviral envelope gene with fusogenic activity and placenta-specific expression in the rabbit: a new "syncytin" in a third order of mammalsSemantic proximity Read ↗

A novel human endogenous retroviral protein inhibits cell-cell fusionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.