Article
Transcriptomic profiling of trophoblast fusion using BeWo and JEG-3 cell lines
29 Oct 2019
Abstract excerpt
In human placenta, alteration in trophoblast differentiation has a major impact on placental maintenance and integrity. However, little is known about the mechanisms that control cytotrophoblast fusion. The BeWo cell line is used to study placental function, since it forms syncytium and secretes hormones after treatment with cAMP or forskolin. In contrast, the JEG-3 cell line fails to undergo substantial fusion....
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