Article

Capture-based DNA methylation sequencing facilitates diagnosis and reveals potential pathogenic mechanisms in teratogenic diabetes exposure

2017-08-04

Abstract excerpt

<h4>ABSTRACT</h4> Diabetic embryopathy (DE) describes a spectrum of birth defects associated with a teratogenic exposure to maternal diabetes in utero. These defects strongly overlap the phenotypes of known genetic syndromes; however, the pathogenic mechanisms underlying DE remain uncertain and there are no definitive tests that distinguish the diagnosis. Here, we explore the potential of DNA methylation as both...

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Literature Corpus work: 9e840aaa-349f-5e0c-9f9b-db23e292567f
DOI: 10.1101/172262

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