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A Mathematical Model of Mitochondria in Proximal Tubule and Thick Ascending Limb Cells

2021-12-19

Abstract excerpt

Mitochondria are a key player in several kinds of tissue injury, and are even the ultimate cause of certain diseases. In this work we introduce new models of mitochondrial ATP generation in multiple tissues, including liver hepatocytes and the medullary thick ascending limb in the kidney. Using this model, we predict these tissues’ responses to hypoxia, uncoupling, ischemia-reperfusion, and oxidative phosphorylati...

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Literature Corpus work
9e731820-628c-5d07-8f47-a408b88e909f
DOI
10.1101/2021.12.16.473049
Open publication

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A Mathematical Model of Mitochondria in Proximal Tubule and Thick Ascending Limb CellsDOI 10.1101/2021.12.16.473049
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