Article

Transposable Element Expression and Sub-cellular Dynamics During hPSC Differentiation to Endoderm, Mesoderm, and Ectoderm Lineages

2024-07-06

Abstract excerpt

Transposable elements (TEs) are genomic elements that are found in multiple copies in mammalian genomes. TEs were previously thought to have little functional relevance but recent studies have reported TE roles in multiple biological processes, particularly in embryonic development. To investigate the expression dynamics of TEs during human early development, we used long-read sequence data generated from in vitr...

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Literature Corpus work: 60bf9407-d7ea-57ee-af6d-75bd323469f6
DOI: 10.1101/2024.07.03.602001

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