Article

Bezafibrate Improves Mitochondrial Fission and Function in DNM1L Deficient Patient Cells

2019-08-08

Abstract excerpt

Mitochondria are involved in many cellular processes and their main role is cellular energy production. They constantly undergo fission and fusion, and these counteracting processes are under strict balance. The cytosolic dynamin-related protein 1, Drp1 or dynamin-1-like protein (DNM1L) mediates mitochondrial and peroxisomal division. Defects in the DNM1L gene results in a complex neurodevelopmental disorder with...

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Literature Corpus work: 9e59eb37-a31d-5eda-845b-4ba77c725228
DOI: 10.20944/preprints201908.0101.v1

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