Article

mtRBP complex AMG-1/SLRP-1 mediates germline development and spermatogenesis by maintaining mitochondrial homeostasis in Caenorhabditis elegans

2022-10-14

Abstract excerpt

<title>Abstract</title> The RNA-binding proteins (RBPs)-mediated post-transcriptional regulation of pre-existing mRNAs is essential for spermatogenesis. But the underlying mechanisms remain poorly understood. Here, we identify a germline-specific mitochondrial RBP<italic> </italic>AMG-1, a homolog of mammalian LRPPRC, required for spermatogenesis in <italic>C. elegans</italic>. <italic>amg-1</italic> mutation...

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Literature Corpus work: 9e2fcc85-6a8e-504b-a5c3-c76ec430438f
DOI: 10.21203/rs.3.rs-2162150/v1

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