Article

Amyloid beta 42 alters cardiac metabolism and impairs cardiac function in obesity

2022-10-05

Abstract excerpt

<h4>ABSTRACT</h4> There are epidemiological associations between obesity and type 2 diabetes, cardiovascular disease and Alzheimer’s disease. While some common aetiological mechanisms are known, the role of amyloid beta 42 (Aβ 42 ) in these diverse chronic diseases is obscure. Here we show that adipose tissue releases Aβ 42 , which is increased from adipose tissue of obese mice and is associated with higher pla...

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Literature Corpus work: 9e02cbc4-2b75-5ee6-b289-835ac236c401
DOI: 10.1101/2022.10.02.510555

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