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Article

Epicardial Adipose Tissue in Myocardial Disease: From Physiology to Heart Failure Phenotypes.

Current problems in cardiology - 1 Oct 2023

Antonopoulos Alexios S, Papastamos Charalampos, Cokkinos Dennis V, Tsioufis Konstantinos, Tousoulis Dimitris

Abstract excerpt

Epicardial adipose tissue (EAT) is increasingly being recognized as a determinant of myocardial biology. The EAT-heart crosstalk suggests causal links between dysfunctional EAT and cardiomyocyte impairment. Obesity promotes EAT dysfunction and shifts in secreted adipokines which adversely affect cardiac metabolism, induce cardiomyocyte inflammation, redox imbalance and myocardial fibrosis. Thus, EAT determines...

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Identifiers

PMID: 37244513
DOI: 10.1016/j.cpcardiol.2023.101841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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