Back to search

Article

A population-based cohort study to establish clinical characteristics and outcomes of patients experiencing methicillin-sensitive <i>Staphylococcus aureus</i> bacteremia as a function of the cefazolin high inoculum effect

2025-12-04

Abstract excerpt

<h4>Background</h4> Staphylococcus aureus bacteremia is a leading cause of morbidity and mortality. Several phenotypes (e.g. methicillin-resistance) influence patient outcomes. The high inoculum effect (HIE) is characterized by reduced susceptibility to beta-lactam antibiotics, most notably cefazolin, at high inoculums in-vitro . <h4>Methods</h4> A population-based cohort was used to assess all MSSA bacteremia...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
9df325f7-2203-5652-a6c4-5f3e92bd12e7
DOI
10.64898/2025.12.03.25341560
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A population-based cohort study to establish clinical characteristics and outcomes of patients experiencing methicillin-sensitive <i>Staphylococcus aureus</i> bacteremia as a function of the cefazolin high inoculum effectDOI 10.64898/2025.12.03.25341560
Association between the blaZ gene and the cefazolin inoculum effect among bloodstream isolates of methicillin-susceptible Staphylococcus aureus.Semantic proximity
Prevalence of blaZ gene types and the cefazolin inoculum effect among methicillin-susceptible Staphylococcus aureus blood isolates and their association with multilocus sequence types and clinical outcome.Semantic proximity
Validation of a modified rapid test to detect the cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus from bloodstream infections in hospitals from North and Latin AmericaSemantic proximity
The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in EnterobacteralesSemantic proximity
Investigation of the cefazolin inoculum effect in blood culture-isolated methicillin-susceptible Staphylococcus aureus strains: A Japanese multicenter study.Semantic proximity
Development of a Rapid Diagnostic Test for the Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus: Cefinase Disk Direct (CDD) testSemantic proximity
Association between Type A blaZ Gene Polymorphism and Cefazolin Inoculum Effect in Methicillin-Susceptible Staphylococcus aureus.Semantic proximity
Antimicrobial resistance determinants are associated with <i>Staphylococcus aureus</i> bacteraemia and adaptation to the hospital environment: a bacterial genome-wide association studySemantic proximity
Select a neighboring publication to make it the new centre.