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Article

Association between the blaZ gene and the cefazolin inoculum effect among bloodstream isolates of methicillin-susceptible Staphylococcus aureus.

Journal of global antimicrobial resistance - 1 May 2026

Zhu Wenyan, Yang Qing, Xiao Yanyan, Jia Huiqiong, Chen Yuqing, Gu Yaxi, Li Shengchao, Qu Yahong

Abstract excerpt

OBJECTIVE: Investigating the incidence of the cefazolin inoculum effect (CzIE) in methicillin-susceptible Staphylococcus aureus and its correlation with the blaZ gene. METHODS: Genotyping and blaZ gene detection using Sanger sequencing were conducted on 113 methicillin-susceptible S. aureus (MSSA) isolates from bloodstream infections at a tertiary hospital in Hangzhou, Zhejiang Province, collected from January...

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PMID: 41802672
DOI: 10.1016/j.jgar.2026.02.012

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