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The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in Enterobacterales

2023-05-23

Abstract excerpt

Carbapenem-resistant Enterobacterales (CRE) are important pathogens that can develop resistance via multiple molecular mechanisms, including hydrolysis or reduced antibiotic influx. Identifying these mechanisms can improve pathogen surveillance, infection control, and patient care. We investigated, both phenomenologically and mechanistically, how resistance mechanisms influence the carbapenem inoculum effect (IE),...

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Literature Corpus work
6ddb0801-f98b-569c-9064-cf055d6f8d20
DOI
10.1101/2023.05.23.541813
Open publication

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The carbapenem inoculum effect provides insight into the molecular mechanisms underlying carbapenem resistance in EnterobacteralesDOI 10.1101/2023.05.23.541813
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