Article

Glucocorticoids inhibit type I IFN beta signaling and the upregulation of CD73 in human lung

2020-04-06

Abstract excerpt

<h4>Purpose</h4> Glucocorticoids are widely used to treat acute respiratory distress syndrome (ARDS) despite its use is highly controversial based on randomized controlled trials and meta-analyses. As type I interferons (IFNs) are our first line of defense against severe viral respiratory infections, we explored whether glucocorticoids interfere with IFN signaling and whether their use associates to outcome of IFN...

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Literature Corpus work: 9dd40297-5099-5ccb-8714-5e53a446ba76
DOI: 10.1101/2020.04.01.20049700

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