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EVA1A Plays an Important Role by Regulating Autophagy in Physiological and Pathological Processes

8 Jun 2021

Abstract excerpt

Eva-1 homolog A (EVA1A) is regarded as TMEM166 (transmembrane protein 166) or FAM176A (family with sequence similarity 176) and a lysosome and endoplasmic reticulum-associated protein involved in regulating autophagy and apoptosis. EVA1A regulates embryonic neurogenesis, cardiac remodeling, islet alpha-cell functions, acute liver failure, and hepatitis B virus replication. However, the related mechanisms are not...

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PMID: 34201121
DOI: 10.3390/ijms22126181

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