Article

Synergistic anti-tumor activity of EGFR inhibition and C/EBPβ antagonism in GBM

2026-04-21

Abstract excerpt

Glioblastoma (GBM) is the most prevalent primary brain cancer, with poor prognosis and limited therapeutic options available. The genetic and cellular heterogeneity characteristic of GBM contributes to poor response rates. Activating mutations of the epidermal growth factor receptor (EGFR) gene are among the most frequent alterations in GBM, occurring in roughly half of cases. Despite the prevalence of EGFR mutati...

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Literature Corpus work: 9d98d5bd-df97-5637-b507-0a2447ce30c9
DOI: 10.64898/2026.04.17.719281

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