Article

Human genetic factors associated with pneumonia susceptibility, a cue for COVID-19 mortality

2021-06-04

Abstract excerpt

The risk for community acquired pneumonia (CAP) is partially driven by genetics. To identify the CAP-associated genetic risk loci, we performed a meta-analysis of clinically diagnosed CAP (3,310 individuals) with 2,655 healthy controls. The findings revealed CYP1A1 variants (rs2606345, rs4646903, rs1048943) associated with pneumonia. We observed rs2606345 [G vs T; OR=1.49(1.29-1.69); p=0.0001; I 2 = 15.5%], and rs...

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Literature Corpus work: 9d906642-7b22-5ed6-a3a5-035fba4d53f1
DOI: 10.1101/2021.06.03.21258106

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