Genetic dissection of host immune response in pneumonia development and progression.

doi:10.1038/srep35021

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Article

Genetic dissection of host immune response in pneumonia development and progression.

Scientific reports - 11 Oct 2016

Smelaya Tamara V, Belopolskaya Olesya B, Smirnova Svetlana V, Kuzovlev Artem N, Moroz Viktor V, Golubev Arkadiy M, Pabalan Noel A, Salnikova Lyubov E

Abstract excerpt

The role of host genetic variation in pneumonia development and outcome is poorly understood. We studied common polymorphisms in the genes of proinflammatory cytokines (IL6 rs1800795, IL8 rs4073, IL1B rs16944), anti-inflammatory cytokines (IL10 rs1800896, IL4 rs2243250, IL13 rs20541) and toll-like receptors (TLR2 and , TLR4 , TLR9 , and ) in patients with...

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PMID: 27725770
DOI: 10.1038/srep35021
PMCID: PMC5057148

Genes

TLR2
TLR4
TLR9

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