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Article

Human genetic factors associated with pneumonia risk, a cue for COVID-19 susceptibility.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2022

Guin Debleena, Yadav Saroj, Singh Priyanka, Singh Pooja, Thakran Sarita, Kukal Samiksha, Kanojia Neha, Paul Priyanka Rani, Pattnaik Bijay, Sardana Viren, Grover Sandeep, Hasija Yasha, Saso Luciano, Agrawal Anurag, Kukreti Ritushree

Abstract excerpt

Pneumonia, an acute respiratory tract infection, is one of the major causes of mortality worldwide. Depending on the site of acquisition, pneumonia can be community acquired pneumonia (CAP) or nosocomial pneumonia (NP). The risk of pneumonia, is partially driven by host genetics. CYP1A1 is a widely studied pulmonary CYP family gene primarily expressed in peripheral airway epithelium. The CYP1A1 genetic variants,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35545162
DOI: 10.1016/j.meegid.2022.105299
PMCID: PMC9080029

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