Article
Genetic susceptibility to nosocomial pneumonia, acute respiratory distress syndrome and poor outcome in patients at risk of critical illness.
Inflammation - 1 Apr 2014
Salnikova Lyubov E, Smelaya Tamara V, Vesnina Irina N, Golubev Arkadiy M, Moroz Viktor V
Abstract excerpt
Genetic susceptibility may partially explain the clinical variability observed during the course of similar infections. To establish the contribution of genetic host factors in the susceptibility to critical illness, we genotyped 750 subjects (419 at high risk of critical illness) for 14 single nucleotide polymorphisms (SNPs) in the xenobiotics detoxification/oxidative stress and vascular homeostasis metabolic...
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