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Article

Functional polymorphisms in the CYP1A1, ACE, and IL-6 genes contribute to susceptibility to community-acquired and nosocomial pneumonia.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jun 2013

Salnikova Lyubov E, Smelaya Tamara V, Moroz Viktor V, Golubev Arkadiy M, Rubanovich Alexander V

Abstract excerpt

OBJECTIVES: To establish the contribution of genetic host factors to the risk of community-acquired pneumonia (CAP) and nosocomial pneumonia (NP) in the population of the Russian Federation. METHODS: A total of 796 subjects (CAP: 334 patients, 134 controls; NP: 216 critically ill patients with NP, 105 critically ill patients without NP) were included in two case-control studies. We analyzed 13 polymorphisms in 11...

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Source

Identifiers

PMID: 23411129
DOI: 10.1016/j.ijid.2013.01.005

Genes

ACE
ABCB1
CCR5
GSTM1
GSTT1
MBL2
MTHFR
NOS3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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