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Article

Genetic risk factors for pneumonia differ by patient subgroup.

EBioMedicine - 1 Feb 2026

Heikkilä Anni, Sliz Eeva, Väyrynen Sara, Reis Kadri, Elnahas Abdelrahman G, Reigo Anu, Esko Tõnu, Kettunen Johannes, Hautala Timo

Abstract excerpt

BACKGROUND: Pneumonia risk is influenced by demographics, chronic disease burden, lifestyle, and environmental factors. Despite previous genetic studies, the impact of host genetics on pneumonia, particularly within specific patient groups, remains unclear. METHODS: We conducted genome-wide meta-analyses of pneumonia using data from FinnGen and Estonian biobank, analysing both the general population and patient...

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Asthma
Case-Control Studies
Child
Child, Preschool
Estonia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genome-Wide Association Study

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Identifiers

PMID: 41579494
DOI: 10.1016/j.ebiom.2026.106136
PMCID: PMC12860974

Genes

CRP
CHRNA5
MUC5AC
CHRNA2
EML6
HNF1A
MUC5B
PTGER4
PTPN22
TNFSF15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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