Article

scAgeCom: a murine atlas of age-related changes in intercellular communication inferred with the package scDiffCom

2021-08-15

Abstract excerpt

Dysregulation of intercellular communication is a well-established hallmark of aging. To better understand how this process contributes to the aging phenotype, we built scAgeCom, a comprehensive atlas presenting how cell-type to cell-type interactions vary with age in 23 mouse tissues. We first created an R package, scDiffCom, designed to perform differential intercellular communication analysis between two condit...

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Literature Corpus work: 01365ca4-b64d-5ec5-b096-ff686e70b6ec
DOI: 10.1101/2021.08.13.456238

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