Article
Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease
2020-12-31
Abstract excerpt
<title>Abstract</title> <p>Congenital heart defects (CHD) constitute the most common birth defect in humans, affecting approximately 1% of all live births. Our ability to understand how these disorders originate is hindered by our limited ability to model the complexity of the human heart in vitro. There is a pressing need to develop more faithful organ-like platforms recapitulating complex in vivo phenotypes to...
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Identifiers and source
- Literature Corpus work
- 74e60b23-68b5-50c3-b6e9-b707d54ba1d1
- DOI
- 10.21203/rs.3.rs-132349/v1