Article

CD2AP Positively Regulates TGF-β1/Smad3-Mediated EMT via TβRI: A Novel Oncogenic Axis Driving Hepatocellular Carcinoma Progression

2026-05-22

Abstract excerpt

<title>Abstract</title> <p> Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related death worldwide, underscoring the urgent need to identify novel drivers of its progression. We investigated the oncogenic role and molecular mechanism of CD2AP in HCC. Analysis of clinical cohorts showed that CD2AP is markedly overexpressed in HCC tissues and that its upregulation correlates with advanced tumour...

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Literature Corpus work: 9cf468dd-c4fe-5678-b39b-de756393d12b
DOI: 10.21203/rs.3.rs-9398634/v1

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CD2AP Positively Regulates TGF-β1/Smad3-Mediated EMT via TβRI: A Novel Oncogenic Axis Driving Hepatocellular Carcinoma ProgressionDOI 10.21203/rs.3.rs-9398634/v1Read

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