Article

Transcription factor JUNB is required for transformation of EpCAM-positive hepatocellular carcinoma (HCC) cells into CD90-positive HCC cells in vitro

2024-10-24

Abstract excerpt

<title>Abstract</title> <p>Hepatocellular carcinoma (HCC) harbors two types of stem cells—epithelial and mesenchymal stem cells. The mechanism by which epithelial EpCAM-positive HCC cells transform into mesenchymal CD90-positive HCC cells remains unclear. On peritumoral fibrotic nodules, epithelial HCC cells form communities with stromal cells, driving tumor growth and malignancy. We aimed to clarify the mechanis...

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Literature Corpus work: af600734-aafc-5c81-822a-9daaeee85276
DOI: 10.21203/rs.3.rs-5134174/v1

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