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Peptide‑Based Therapeutics Targeting the SLC39A14‑PIWIL2 Fusion in Hepatocellular Carcinoma

2025-08-14

Abstract excerpt

<title>Abstract</title> <p>Fusion genes are key oncogenic drivers in various cancers, yet their role in hepatocellular carcinoma (HCC) remains underexplored. To identify fusion genes contributing to HCC progression, we analyzed RNA-seq data from HCC patients and identified SLC39A14-PIWIL2 as a novel putative driver. Functional assays revealed that the SLC39A14 promoter induces overexpression of a truncated PIWIL2...

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Literature Corpus work
8f1e1c79-1362-5cfb-85d9-1e5ebeb32237
DOI
10.21203/rs.3.rs-7217926/v1
Open publication

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Peptide‑Based Therapeutics Targeting the SLC39A14‑PIWIL2 Fusion in Hepatocellular CarcinomaDOI 10.21203/rs.3.rs-7217926/v1
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