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Inhibition of host <i>N</i> -myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum

2023-03-03

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, remains a global health concern despite vaccines, neutralizing antibodies, and antiviral drugs. Emerging mutations can reduce the effectiveness of these treatments, suggesting that targeting host cell factors may be a valuable alternative. N -myristoyltransferases (NMT) are essential enzyme...

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Literature Corpus work
9ca07e28-bd57-5ae7-b9c9-89e7e48bad79
DOI
10.1101/2023.03.03.530798
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Inhibition of host <i>N</i> -myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulumDOI 10.1101/2023.03.03.530798
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